Logo

Swift Biosciences Announces New Industry-Leading Indexed Adapters for Sequencing Larger Numbers of Samples in a Single Run

Category: General News
Posted Aug 4, 2017 06:49 (GMT +7)

Revolutionary technology will accelerate utility of gene mapping, biomarker discovery, tumor profiling, and liquid biopsy analysis

ANN ARBOR, Mich.--(BUSINESS WIRE)--Aug. 03, 2017

Swift Biosciences, a leading provider of innovative library prep solutions for genomic sequencing, today announced the launch of Accel-NGS® 2S Indexed Adapters, a new portfolio of indices that significantly improves multiplexed next-generation sequencing on Illumina® platforms. This unique set of indices provides the largest set of commercially available, single indices for high-throughput genomic sequencing applications, enabling users to reliably multiplex up to 96 single-indexed samples and 768 dual-indexed samples per run. This industry-leading technology meets the growing demand from research and core laboratories to pool greater sample numbers per instrument run, enabling more economical sequencing while providing better data accuracy.

Multiplex DNA sequencing is a common workflow in which multiple samples are labeled and pooled together into a single run to increase throughput and to reduce sequencing cost per sample. Recent peer-reviewed publications have shown other commercially available indices are impacted by multiplexing errors, called “index hopping”—the misassignment of sequencing reads to the wrong sample. Additionally, older multiplex DNA sequencing technologies are prone to other sequencing errors, compounding the misassignment error rates. As sequencing platforms increase capacity, such as Illumina’s newest platform, NovaSeq™, the need for high stringent indices to enable large numbers of samples to be multiplexed is in large demand.

Researchers at Swift Biosciences said its Accel-NGS 2S Indexed Adapters are a set of 96 single indices optimized to work in combination with Illumina TruSeq® P5 adapters to provide up to 768 unique dual-index combinations. These new indices are optimized to provide greater flexibility to process between 96-768 uniquely tagged samples per run and can accommodate a wider range of projects with varying sequencing depth. Additionally, the unique design eliminates misassignment and index hopping, an issue specific to Illumina’s pattern flow cells. These improvements provide greater sensitivity to detect low frequency variants as well as greater fidelity to accelerate de-multiplexing during data analysis.

“Our goal at Swift is to enable scientists to generate the highest quality data from any sample type, letting them push the boundaries of their science,” stated Timothy Harkins, president and CEO of Swift Biosciences. “Our new Accel-NGS 2S Indexed Adapters close the throughput and cost gap on Illumina platforms, and when combined with Accel-NGS 2S technologies, all types of sequencing laboratories are generating higher quality data in a much more cost-effective manner.”

First Commercial Order

The new Accel-NGS 2S Indexed Adapters are commercially available now. The first commercial order shipped to Shanghai Nanodigmbio Biotechnology Co. LTD, a distribution channel partner for Swift’s product portfolio in China. Shanghai Nanodigmbio Biotechnology is one of the fastest growing sequencing markets and a critical player in genomics and disease research. In 2016, China unveiled its “Five-Year Plan” with a strategic focus on precision medicine, a rapidly growing focal area of genomics that will guide future diagnostic and therapeutic development.

“Swift’s new indexed adapters provide a major advantage to researchers conducting target enrichment sequencing,” said Chance Wu, CEO of Shanghai Nanodigmbio Biotechnology Company. “Now it will be possible for researchers to maximize the number of exomes per run to rapidly survey larger sample sets in a more cost-effective manner.”

View source version on businesswire.com: http://www.businesswire.com/news/home/20170803006256/en/

Contact:

Lambert, Edwards & Associates
Darby Wagner, (616) 258-5779
dwagner@lambert-edwards.com

Distribute your news release with us

  • Print

    unique advertising solution

    Our media lists include news desks at all leading Thai and English-language dailies.

  • Radio & TV

    reliable platform

    We deliver your news to leading Thai radio stations and TV channels.

  • Internet Sites

    cloud computing

    All releases are submitted to Internet news sites, including several with guaranteed pickup.

Our Self-Serve News Release Couldn't Be Simpler

Our streamlined online process makes it simple and fast to submit your news to the Thai media. Once registered, just enter or copy your text into our submission form and you'll see an instant preview with our fee based on the word count, translation, and any attached image. To confirm submission, hit Enter to be taken to our payment processor. Once payment is approved, your release passes automatically to our news desk for translation and dissemination by our skilled and experienced team. You'll be kept informed at each step of the process.

Do NOT follow this link or you will be banned from the site!